Phased T2T genome assemblies facilitate the mining of disease-resistance genes in Vitis davidii.

ABSTRACT: Grape is an important fruit crop, and its production faces significant threat from diseases, resulting in substantial economic loss. Wild grape relatives are valuable resources for the restoration of disease-resistance loci. However, available resistance loci in wild grape genomes remain largely unexplored. In this study, we assembled two phased genomes, including a high-resistant Chinese wild grape, Vitis davidii Föex, and a susceptible cultivar, Vitis vinifera L. cv. 'Manicure Finger'. We detected a total of 36 688 structural variations (SVs), with the genes associated with heterozygous SVs showing an enrichment in allele-specific expression (ASE). Furthermore, we identified eight subgroups of R genes and found that 74.2% of R genes overlap with transposable elements (TEs).

SUBMITTER: Luo Y 

PROVIDER: S-EPMC11817892 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature