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Early Prediction of Fetal Macrosomia Through Maternal Lipid Profiles.


ABSTRACT: The prevalence of fetal macrosomia is steadily increasing worldwide, reaching up to 20%. Fetal macrosomia complicates pregnancy and delivery. Current prediction strategies are inaccurate, and most patients with fetal macrosomia go into labor with an "unknown status". The aim of this study was to develop a system for predicting fetal macrosomia based on the lipid profiles of pregnant women's blood serum. In total, 110 patients were included in this study: 30 patients had gestational diabetes mellitus (GDM) and 80 did not. During the observation, blood samples were collected at three time points: in the first trimester (11-13 weeks of pregnancy), in the second trimester (24-26 weeks), and in the third trimester (30-32 weeks). Lipids were detected by flow injection analysis with mass spectrom

SUBMITTER: Chagovets V 

PROVIDER: S-EPMC11818448 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature