Continuous Monitoring Enables Dynamic Biomarkers to Assess Resilience in Acute COVID-19 Patients.

ABSTRACT: Background/Objectives: The effective management of acute illnesses like COVID-19 requires tools to dynamically assess a patient's resilience to health stressors. This study evaluates novel dynamic biomarkers from continuous blood oxygen saturation (SpO₂) monitoring, exploring their association with patient outcomes to support clinical decision making. Methods: We examined 200 hospital admissions from 181 adults diagnosed with COVID-19. Two dynamic biomarkers reflecting the homeostatic regulation efficiency of SpO₂ were developed to assess their association with adverse hospital outcomes, specifically ICU admission or death, using binary logistic regressions. The resilience exponent α recorded the relative frequency of prolonged SpO₂ declines,

SUBMITTER: Rector JL 

PROVIDER: S-EPMC11818652 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature