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Brain Imaging in Patients with Non-Small Cell Lung Cancer-A Systematic Review.


ABSTRACT: Background: Lung cancer frequently metastasizes to the brain, liver, and adrenal glands with a significant negative prognostic impact on overall survival and quality of life (QoL). To optimize treatment and prognosis, adequate staging with the detection of distant metastases is crucial. The incidence of brain metastases in potentially resectable early-stage non-small cell lung cancer (NSCLC) is as low as 3%; hence, the need for preoperative brain imaging has been a constant matter of debate, especially in stage II. In stages III and IV NSCLC, neuroimaging is an essential part of staging. Methods: A systematic literature search was performed. Publications from 1999 to 2024, focusing on preoperative brain imaging (BI) in the staging of stages I-IV NSCLC, were included. Data ext

SUBMITTER: Mayer N 

PROVIDER: S-EPMC11818832 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature