PM_2.5 threshold exceedances during the prenatal period and risk of intellectual disability.

ABSTRACT:

Background

Research demonstrates that chronic exposure to fine particulates (PM_2.5) increases risks of neurodevelopmental conditions, such as intellectual disability (ID). Few studies have examined neurodevelopmental health impacts of pollution spikes exceeding 24-h (24-h) PM_2.5 guidelines, despite relevance to the regulatory landscape. The current potential for regulatory changes to 24-h PM_2.5 standards in the United States makes research on exceedances relevant.

Objective

To examine associations between 24-h PM_2.5 exceedances and the risk of ID.

Methods

We conducted a retrospective case-control study of a sample of children in Utah, USA. We used generalized estimating equations to predict odds of ID based on the number of

SUBMITTER: Grineski SE 

PROVIDER: S-EPMC11818943 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature