CT imaging biomarkers to predict severity and prognosis of pulmonary hypertension.

ABSTRACT:

Purpose

To explore whether there are computed tomography (CT) imaging biomarkers that can stratify the severity of patients with pulmonary hypertension (PH).

Methods

We retrospectively enrolled 144 consecutive patients with suspected PH who underwent CT pulmonary angiography and right heart catheterization (RHC). CT findings were analyzed by two observers for large vessel size [ascending aorta (A), pulmonary artery (P), inferior vena cava (IVC)], each chamber size, and septal angle. We investigated the associations between CT imaging parameters and the mean pulmonary artery pressure (mPAP) from RHC. During a median follow-up of 36 months, we observed major adverse cardiovascular events (MACE; all-cause mortality and hospitalization for PH worsening). Univariate and multivari

SUBMITTER: Yoon DW 

PROVIDER: S-EPMC11819466 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature