Association between mixed venous oxygen saturation and serum uric acid levels in patients with heart failure.

ABSTRACT: Hypoxia leads to increased purine metabolism in tissues, resulting in increased serum uric acid levels, and may also cause impaired uric acid excretion in the kidneys and intestinal tract. However, the relationship between hypoxia and serum uric acid levels in patients with heart failure remains largely unexplored. Because mixed venous oxygen saturation is an acute indicator of systemic oxygenation, in this study, we investigated the relationship between mixed venous oxygen saturation and serum uric acid levels. This retrospective analysis included 386 patients with heart failure who underwent cardiac catheterization at our institution. The relationship between mixed venous oxygen saturation and serum uric acid levels was examined by single regression analysis. Stratified regression analys

SUBMITTER: Mashitani Y 

PROVIDER: S-EPMC11819564 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature