Patterns of failure with ¹⁸F-DCFPyL PSMA-PET/CT in the post-prostatectomy setting A regional cohort analysis.

ABSTRACT:

Introduction

This study aimed to assess the detection rate of prostate cancer recurrence by prostate-specific member antigen-positron emission tomography/computed tomography (PSMA-PET/CT) with ¹⁸F-DCFPyL in patients with residual disease or biochemical recurrence (BCR), and its association with surgical pathology and prostate-specific antigen (PSA) kinetics.

Methods

Men from South Central Ontario enrolled in the PSMA Registry for Recurrent Prostate cancer (PREP) between April 2019 and December 2021 after radical prostatectomy (RP) and who had 1) pathologic stage N1 or persistent elevated PSA; or 2) BCR (PSA ≥0.10 ng/mL) where initial postoperative PSA was undetectable were included.

Results

A total of 169 men (median age 68 years; interquartile range [IQR]

SUBMITTER: Sigurdson S 

PROVIDER: S-EPMC11819851 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature