Anti-Inflammatory, Anti-Hyperglycemic, and Anti-Aging Activities of Aqueous and Methanolic Fractions Obtained from <i>Cucurbita ficifolia</i> Bouche Fruit Pulp and Peel Extracts.

ABSTRACT: The Cucurbita genus comprises various species that are globally consumed and that are commonly used for their nutritional value but also for medicinal applications. Within the Cucurbita genus can be found Cucurbita ficifolia Bouché, a species that is understudied regarding its potential value for the food industry, as a functional food, and for the pharmaceutical industry, as a source of nutraceuticals. Therefore, in this study we investigated the phytochemical composition and bioactivities of aqueous (AF) and methanolic (MF) fractions of C. ficifolia pulp and peel hydroethanolic (HE) extracts. HPLC-DAD-MSⁿ and HPAEC-PAD analyses of extracts' fractions revealed a low content of polyphenols and a significant content of sugars. Through in vitro inhibiti

SUBMITTER: Coutinho TE 

PROVIDER: S-EPMC11819910 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature