Rapid Identification of Constituents in <i>Polygonatum cyrtonema</i> Hua Using UHPLC-Q-Exactive Orbitrap Mass Spectrometry.

ABSTRACT: Polygonatum cyrtonema Hua (PCH) belongs to the genus Polygonatum Mill of the Liliaceae family. As a traditional tonic herb, the rhizome of PCH has been widely used as a functional food and traditional Chinese medicine, mainly for the treatment of spleen and lung Qi deficiency, essence and blood deficiency, internal heat, and thirst. To further elucidate the unknown chemical composition of PCH, this study presents an analytical strategy using macroporous resin (D101) column chromatography combined with ultra-high-performance liquid chromatography-Q-Exactive Orbitrap mass spectrometry (UHPLC-Q-Exactive Orbitrap MS) for the characterization of PCH's chemical composition. The PCH extracts were separated via D101 resin column chromatography in conjunction with reverse phase liquid chroma

SUBMITTER: Yang Q 

PROVIDER: S-EPMC11819922 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature