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<i>N</i>,<i>N</i>-Dimethylformamide's Participation in Domino Reactions for the Synthesis of Se-Phenyl Dimethylcarbamoselenoate Derivatives.


ABSTRACT: N,N-dimethylformamide's (DMF) participation in domino reactions has been developed. Starting from substituted halogenobenzenes and selenium powder, versatile biologically active Se-phenyl dimethylcarbamoselenoate derivatives were efficiently synthesized under mild reaction conditions. The reaction mechanism was studied using control experiments. These protocols involve a wider substrate scope and provide an economical approach toward C-selenium bond formation.

SUBMITTER: Xu R 

PROVIDER: S-EPMC11820005 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature