Chloride and Acetonitrile Ruthenium(IV) Complexes: Crystal Architecture, Chemical Characterization, Antibiofilm Activity, and Bioavailability in Biological Systems.

ABSTRACT: Due to the emergence of drug resistance, many antimicrobial medications are becoming less effective, complicating the treatment of infections. Therefore, it is crucial to develop new active agents. This article aims to explore the ruthenium(IV) complexes with the following formulas: (Hdma)₂(HL)₂[Ru^IVCl₆]·2Cl·2H₂O (1), where Hdma is protonated dimethylamine and L is 2-hydroxymethylbenzimidazole, and [Ru^IVCl₄(AN)₂]·H₂O (2), where AN is acetonitrile. This paper delves into the physicochemical characteristics and crystal structures of these complexes, employing various techniques such as spectroscopy (IR, UV-Vis), electrochemistry (CV, DPV), and X-ray crystallography. Hirshfeld surf

SUBMITTER: Jablonska-Wawrzycka A 

PROVIDER: S-EPMC11820517 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature