Dairy Consumption and the Colonic Mucosa-Associated Gut Microbiota in Humans-A Preliminary Investigation.

ABSTRACT:

Background

Dairy consumption has been associated with various health outcomes that may be mediated by changes in gut microbiota.

Methods

This cross-sectional study investigated the association between the colonic mucosa-associated gut microbiota and the self-reported intake of total dairy, milk, cheese, and yogurt. A total of 97 colonic mucosal biopsies collected from 34 polyp-free individuals were analyzed. Dairy consumption in the past year was assessed using a food frequency questionnaire. The 16S rRNA gene V4 region was amplified and sequenced. Operational taxonomic unit (OTU) classification was performed using the UPARSE and SILVA databases. OTU diversity and relative abundance were compared between lower vs. higher dairy consumption groups. Multivariable negative binom

SUBMITTER: Chen E 

PROVIDER: S-EPMC11820694 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature