Trends and Challenges in Plant Cryopreservation Research: A Meta-Analysis of Cryoprotective Agent Development and Research Focus.

ABSTRACT: The stable long-term preservation of plant cells is crucial for biopharmaceuticals and food security. Therefore, the long-term cryopreservation of plant cells using a cryoprotective agent (CPA) is a crucial area of study. However, research on low-toxicity CPAs remains limited. We analyzed 1643 abstracts related to plant-cryopreservation (PCP) research published from 1967 to May 2023, spanning 56 years, from academic citation databases, with the search conducted in May 2023. Grouping these abstracts by five-year intervals revealed an increase in PCP papers until 2015, followed by a decline in the 2020s. In order to confirm the declining trend, we performed text-mining analysis using the Latent Dirichlet Allocation (LDA) algorithm, which identifies underlying topics across diverse documents

SUBMITTER: Kang P 

PROVIDER: S-EPMC11821117 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature