Evaluation of the Properties of Bioactive Mesoporous Glasses Doped with Cerium and Loaded with Polyphenols.

ABSTRACT: (1) Background: The onset of inflammation and oxidative stress after biomaterial implantation can lead to complications and prolonged recovery times. To address this, bioactive mesoporous glasses doped with cerium (0, 3.6 and 5.3 mol%) were loaded with three different biomolecules-3-hydroxyflavone, quercetin and morin hydrate-to enhance antioxidant properties while preserving bioactivity. (2) Methods: Elemental analysis, specific surface area determination, spectroscopic techniques, evaluation of antioxidant activity and in vitro bioactivity assessment were performed to characterize mesoporous glass loaded with biomolecules. (3) Results: Biomolecule loading gives values in the range of 0.5-2.0% and 10.3-39.6% for loading content and loading efficiency, respectively. The loading order is qu

SUBMITTER: Giordana A 

PROVIDER: S-EPMC11821127 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature