Depth-electrode stimulation and concurrent functional MRI in humans: Factors influencing heating with body coil transmission.

ABSTRACT: Electrical-stimulation fMRI (es-fMRI) combines direct stimulation of the brain via implanted electrodes with simultaneous rapid functional magnetic resonance imaging of the evoked response. Widely used to map effective functional connectivity in animal studies, its application to the human brain has been limited due to safety concerns. In particular, the method requires reliable prediction and minimization of local tissue heating close to the electrodes, which will vary with imaging parameters and hardware configurations. Electrode leads for such experiments typically remain connected to stimulators outside the magnet room and cannot therefore be treated as electrically short at the radio frequencies employed for 1.5 T and 3 T fMRI. The potential for significant absorption and scattering o

SUBMITTER: Oya H 

PROVIDER: S-EPMC11821395 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature