Effects of apple cider vinegar on glycemic control and insulin sensitivity in patients with type 2 diabetes: A GRADE-assessed systematic review and dose-response meta-analysis of controlled clinical trials.

ABSTRACT:

Background and aims

Diabetes mellitus (DM) is a multifactorial metabolic disorder that affects the body's ability to regulate blood sugar levels. Apple cider vinegar (ACV) could possibly improve diabetes; nevertheless, evidences provide conflicting results. This study aimed to evaluate the effects of ACV on glycemic profile in type 2 diabetes patients (T2DM) in controlled trials (CTs) by systematically reviewing and dose-response meta-analysis.

Methods

The Scopus, PubMed, and Web of Science databases were searched until November 2024 according to a systematic approach. All CTs investigating ACV's effects on glycemic factors were included. We used a random-effects model to calculate WMDs and 95% confidence intervals (CIs). The present study assessed publication bias, sensitiv

SUBMITTER: Arjmandfard D 

PROVIDER: S-EPMC11821484 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature