Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.

ABSTRACT: The risk of children being infected with Influenza A virus (IAV) is high, and if not treated promptly, it can lead to serious illness. Compared with control group, IAV infection decreased the contents of platelet, white blood cell, lymphocyte, eosinophil, basophil, CD3⁺ T cells, CD4⁺ T cells, CD8⁺ T cells, and B cells, while increasing the number of red blood cell. Additionally, IAV infection increased serum concentrations of total protein, albumin and lipase, while decreasing the contents of calcium, triglyceride, total bilirubin, direct bilirubin, indirect bilirubin and gamma-glutamyltransferase. However, the interactions between the respiratory microbiome and metabolites and their impact on IAV in children remains unclear. Ultra performance liquid chroma

SUBMITTER: Shi X 

PROVIDER: S-EPMC11821643 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature