Bioinformatics and experimental insights into F2RL1 as a key biomarker in cervical cancer diagnosis and prognosis.

ABSTRACT: Cervical cancer(CCa) remains a significant global public health concern, with early diagnosis and treatment being crucial. Moreover, the molecular mechanisms underlying its pathogenesis remain incompletely elucidated. F2RL1 is closely associated with various tumors. However, its relationship with CCa is poorly understood. We accessed data from 309 patients diagnosed with CCa from TCGA database. The Limma package facilitated differential expression analysis to identify differentially expressed mRNAs (DEmRNAs). Survival analysis and ROC analysis were conducted via the XIANTAO database. Immune-related genes were identified with F2RL1-related genes through ImmPort database analysis. Functional enrichment analysis was carried out using GO, KEGG, and GSEA. We gathered cervical cells and serum fr

SUBMITTER: Dai Y 

PROVIDER: S-EPMC11821865 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature