Spherical lesion formation in HIFU using robotic assistance for controlled focal point manipulation.

ABSTRACT: We propose a robot-assisted method to generate spherical thermal lesions by high-intensity focused ultrasound (HIFU) ablation. Typically, HIFU-induced thermal lesions are cigar-shaped because the acoustic field in the focal area has a similar elongated shape. We assumed that HIFU irradiation with a certain range and pattern of motion could influence the heat transfer within the target area, allowing control over the lesion's shape and size. Based on the simulations of various motion models likely to induce a change of heat transfer pattern around the target area, we identified Gaussian random motion (GRM) as the optimal motion model for generating spherical thermal lesions. In the experiment, the GRM model was tested using a robotic arm on bovine serum albumin (BSA) gels. The transparency

SUBMITTER: Seo J 

PROVIDER: S-EPMC11821867 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature