Association between urinary heavy metal/trace element concentrations and kidney function: a prospective study.

ABSTRACT:

Background

Chronic kidney disease (CKD) is an important public health problem. Although cross-sectional studies have identified many heavy metals/trace elements associated with reduced kidney function, prospective studies are needed to determine the pathogenic role of these elements in the development and progression of CKD.

Methods

To explore the association between baseline urinary heavy metal/trace element concentrations and long-term impaired kidney function (IKF)/CKD, as well as the incidence of rapid decline in kidney function in a population-based exploratory prospective study, with mean age 51.9 years at baseline whose urinary trace elements concentrations have been determined by inductively coupled plasma mass spectrometry. IKF was defined by a reduced estimated glo

SUBMITTER: Xie S 

PROVIDER: S-EPMC11822291 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature