Sepsis in Internal Medicine: blood culture-based subtypes, hospital outcomes, and predictive biomarkers.

ABSTRACT:

Background

Sepsis is a challenging condition increasingly managed in medical wards, however literature and clinical evidence in this hospital setting are lacking.

Methods

Using the computational i2b2 framework, we retrospectively analyzed data from patients admitted to internal medicine units of four hospitals in Lombardy (Italy) between January 2012 and December 2023, with a discharge diagnosis of sepsis, septic shock, or septicemia.

Results

A total of 4,375 patients were recruited. Median length of stay (LOS) was 14 days, and mean ward-to-intensive care unit (ICU) transfer and in-hospital mortality rates were 11 and 26%, respectively; significant differences were observed over the years, with LOS peaks preceding mortality peaks by 1 year. Blood culture-negative seps

SUBMITTER: Zizzo G 

PROVIDER: S-EPMC11822444 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature