Effectiveness of upgrade left bundle branch area pacing for right ventricular pacing-induced cardiomyopathy: Extra QRS shortening matters.

ABSTRACT:

Background and objectives

Left bundle branch area pacing (LBBAP) has developed as a strategy for patients with pacing-induced cardiomyopathy (PICM). We aimed to compare the upgrade effectiveness between LBBAP and traditional biventricular pacing (BVP) in PICM patients.

Methods

Consecutive PICM patients with successful device upgrades were enrolled. The primary outcome was the echocardiographic response, defined as absolute left ventricular ejection fraction (LVEF) improvement ≥5% at 6-month follow up.

Results

A total of 92 patients were included. 61 underwent BVP and 31 underwent LBBAP. The median RVP burden was 96.8% (IQR: 93.0-99.0%). LBBAP achieved a shorter paced QRS duration (QRSd) compared with BVP (145.9 ± 22.4 ms vs. 157.5 ± 26.5 ms; p =.031). At 6 mont

SUBMITTER: Huang H 

PROVIDER: S-EPMC11822657 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature