Brain lesion characteristics in Chinese multiple sclerosis patients: A 7-T MRI cohort study.

ABSTRACT:

Objective

Prevalence, susceptibility genes, and clinical and radiological features may differ across different ethnic groups of multiple sclerosis (MS). We aim to characterize brain lesions in Chinese patients with MS by use of 7-T MRI.

Methods

MS participants were enrolled from the ongoing China National Registry of Neuro-Inflammatory Diseases (CNRID) cohort. 7-T MRI of the brain was performed. Each lesion was evaluated according to a standardized procedure. Central vein sign (CVS) and paramagnetic rim lesions were identified. The characteristics of lesions at patient-level and at lesion-level from previous 7-T MRI literature were also summarized.

Results

We included 120 MS patients. Their mean (SD) age was 34.6 (9.4) years. The female-to-male ratio was 1.7:1 and mea

SUBMITTER: Su L 

PROVIDER: S-EPMC11822798 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature