Morbidity and Mortality of Hospital-Onset SARS-CoV-2 Infections Due to Omicron Versus Prior Variants : A Propensity-Matched Analysis.

ABSTRACT:

Background

Many hospitals have scaled back measures to prevent nosocomial SARS-CoV-2 infection given large decreases in the morbidity and mortality of SARS-CoV-2 infections for most people. Little is known, however, about the morbidity and mortality of nosocomial SARS-CoV-2 infections for hospitalized patients in the Omicron era.

Objective

To estimate the effect of nosocomial SARS-CoV-2 infection on hospitalized patients' outcomes during the pre-Omicron and Omicron periods.

Design

Retrospective matched cohort study.

Setting

5 acute care hospitals in Massachusetts, December 2020 to April 2023.

Patients

Adults testing positive for SARS-CoV-2 on or after hospital day 5, after negative SARS-CoV-2 test results on admission and on hospital day 3, were matched

SUBMITTER: Klompas M 

PROVIDER: S-EPMC11822919 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature