Prognostic prediction of long-term survival in patients with type A aortic dissection undergoing surgical repair: development of a novel prognostic index.

ABSTRACT:

Background

This study developed and investigated the prognostic significance of a comprehensive biomarker for postoperative type A aortic dissection (TAAD) patients.

Methods

A retrospective cohort of 175 TAAD patients who underwent open surgery at the First Affiliated Hospital of Chongqing Medical University, China, between September 2017 to December 2020, was included in the analysis. The least absolute shrinkage and selection operator (LASSO) method was employed to select indicators, thereby constructing a comprehensive biomarker, termed the comprehensive physiological response indicator (CPRI). The prognostic significance of the CPRI was assessed employing the Kaplan-Meier method and log-rank test. Univariate and multivariate Cox regression model were applied to identify

SUBMITTER: Cai H 

PROVIDER: S-EPMC11823025 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature