Tear-fluid-derived biomarkers of ocular complications in diabetes: a systematic review and meta-analysis.

ABSTRACT:

Background

Early identification and management of sight-threatening ocular complications of diabetes using imaging or molecular biomarkers could help prevent vision loss. However, access to specialized infrastructure and expertise is limited, especially in remote areas of the world. Tear-fluid may offer an easier, non-invasive, and localized screenshot of ocular disease. To the best of our knowledge, there is no systematic review and meta-analysis on tear-fluid-based biomarkers for ocular complications in diabetes.

Methods

Articles were extracted from PubMed, Embase, Medline, and Web of Science using the MeSH and Emtree terms. The keywords include (diabetes), (diabetic retinopathy), (diabetes mellitus, type 1), (diabetes mellitus, type 2), (insulin-dependent diabetes), (insu

SUBMITTER: Polkamp M 

PROVIDER: S-EPMC11823092 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature