Deciphering the genetic basis of developmental language disorder in children without intellectual disability, autism or apraxia of speech.

ABSTRACT:

Background

Developmental language disorder (DLD) refers to children who present with language difficulties that are not due to a known biomedical condition or associated with autism spectrum disorder (ASD) or intellectual disability (ID). The clinical heterogeneity of language disorders, the frequent presence of comorbidities, and the inconsistent terminology used over the years have impeded both research and clinical practice. Identifying sub-groups of children (i.e. DLD cases without childhood apraxia of speech (CAS)) with language difficulties is essential for elucidating the underlying genetic causes of this condition. DLD presents along a spectrum of severity, ranging from mild speech delays to profound disturbances in oral language structure in otherwise typically intelligent

SUBMITTER: Ormieres C 

PROVIDER: S-EPMC11823097 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature