Transcriptome and DNA methylation analyses provide insight into the heterosis of growth-related traits in hybrid yellow croaker.

ABSTRACT:

Background

Interspecific hybrid combinations of Larimichthys crocea × Larimichthys polyactis exhibit heterosis in terms of growth traits; however, the molecular regulatory mechanism underlying this phenomenon remains unclear. DNA methylation plays a pivotal role in regulating gene expression and is involved in growth and development processes. In this study, we comprehensively investigated intricate regulatory processes by integrating transcriptome and methylome datasets from brain, liver, and muscle tissues.

Results

We analyzed a total of 72 sequence datasets, including transcriptome and genome-wide DNA methylome data, from 36 tissue samples using LC, LP, LPC and LCP. We elucidated the distinct expression patterns of these four populations and examined their interactions wi

SUBMITTER: Guo DD 

PROVIDER: S-EPMC11823156 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature