ZIP-8/Ag-based size-selective SERS nanoplatform for ultrasensitive urea detection in milk samples: effects of analyte molecular dimensions on adsorption capacity and sensing performance.

ABSTRACT: Being well-known as an excellent sorbent, metal-organic frameworks (MOFs) have been employed to intergrate with noble metal nanoparticles to fabricate active substrates for surface-enhance Raman spectroscopy (SERS) sensing applications. In this work, we employed three organic molecules with different molecular dimensions, including urea, methylene blue (MB) and Congo red (CR) for investigating SERS performance of a ZIP-8/Ag heterostructure. While every dimension of urea is smaller than the pore size of ZIP-8, MB and CR has one dimension larger than that of the pore size. The results show that only urea experienced large SERS enhancements on ZIP-8/Ag sensing platform. In contrast, MB and CR exhibited lower SERS intensity on ZIP-8/Ag than on pure Ag nanoparticle substrates. Adsorption capaci

SUBMITTER: Nga DTN 

PROVIDER: S-EPMC11823638 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature