Nocturnal Light Pollution Synergistically Impairs Glucose Metabolism With Age and Weight in Monkeys.

ABSTRACT: Over the past decades, the global prevalence of Type 2 diabetes mellitus (T2D) and impaired glucose tolerance (IGT) has been increasing at an epidemic rate, yet the exact cause remains unknown. It is widely accepted that glucose metabolism can be impaired by circadian rhythms and sleep disturbances. Concurrently, exposures to light at night have been closely linked to circadian and sleep disturbances. However, there is no direct experiment on primates to demonstrate the precise extent of how serious light pollution impairs glucose metabolism, whether people will eventually become accustomed to this environment, and whether the pollution has synergistic impairing effects with aging and weight on glucose metabolism. To quantitatively address these questions, 137 cynomolgus were exposed to th

SUBMITTER: Wang S 

PROVIDER: S-EPMC11824604 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature