Social and Communication Development in Infants with Isolated Agenesis of the Corpus Callosum.

ABSTRACT:

Objective

To evaluate the development of social behavior, communication, emotion regulation, and repetitive behaviors in infants with congenital malformation of the corpus callosum, specifically those with isolated agenesis of the corpus callosum (ACC), in comparison with infants who are developing typically.

Study design

This case-control longitudinal observation study examined parent report of social behavior, social-communication, emotion regulation, and repetitive behavior development in community-ascertained infants (n = 156) and infants with isolated ACC (n = 57) between 12 and 24 months of age.

Results

Infants with isolated ACC produced fewer words at 12 (P = .003) 18 (P < .001), and 24 months of age (P = .003) and fewer gestures at 12 (

SUBMITTER: Paul LK 

PROVIDER: S-EPMC11824658 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature