Preoperative Ketamine Gargle for Prevention of Postoperative Sore Throat After Tracheal Intubation in Adults: A Meta-Analysis.

ABSTRACT: Objective: This meta-analysis aims to evaluate the impact of preoperative ketamine gargle on postoperative throat pain in patients undergoing general anesthesia with endotracheal intubation (ETI). Methods: A comprehensive search was conducted in databases including PubMed, Cochrane Library, Web of Science, ScienceDirect, Scopus, ClinicalTrials.gov, and others. Data analysis was performed using RevMan 5.4 and Stata Statistical Software 18 (StataCorp., Texas., United States of America). Odds ratio with 95% confidence interval (CI) and mean difference were calculated for outcomes: incidence of postoperative 0, 2, 4, 8, and 24 h sore throat and anesthesia time. The overall certainty of evidence was evaluated with the Grading of Recommendations Assessment, Development and Evaluati

SUBMITTER: Fu S 

PROVIDER: S-EPMC11824847 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature