On-Pump FIBTEM-A5 Accurately Predicts the A5 Values After Protamine Administration.

ABSTRACT: Introduction: In the present study, we aimed to investigate whether the measurements of the fibrinogen-dependent clot firmness in FIBTEM-one of the rotational thromboelastometry (ROTEM) assays-during cardiopulmonary bypass (CPB) accurately predict the values after protamine administration. Materials and Methods: In this single-center retrospective observational study, we analyzed a database of patients undergoing on-pump surgeries between May 2022 and February 2024. We included patients in whom an intraoperative ROTEM examination during CPB and a follow-up examination directly after protamine infusion were performed. We excluded patients who received either fibrinogen concentrate or fresh frozen plasma between the two examinations. FIBTEM A5 values in both examinations were c

SUBMITTER: Vander Zwaag S 

PROVIDER: S-EPMC11824858 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature