Neurological outcomes and associated perinatal factors in infants born between 22 and 25 weeks with active care.

ABSTRACT:

Objectives

To elucidate the outcomes of periviable infants receiving active care (AC) and explore perinatal factors associated with neurodevelopmental outcomes.

Methods

This is a single-center retrospective study on infants born at 22-25 weeks of gestation, all of whom received AC. A developmental quotient (DQ) ≥ 85 at corrected 18 months was judged as normal.

Results

Fifty-seven infants were included in the study. The survival rates at discharge were 83%, 86%, 93%, and 93% at 22, 23, 24, and 25 gestational weeks, respectively. The overall percentage of normal DQ was 26/47 (55%). Acidemia in the arterial blood gas measured within 6 h after birth was identified as a factor significantly associated with subnormal DQ.

Conclusions

Not only high survival rates, but

SUBMITTER: Ariyoshi Y 

PROVIDER: S-EPMC11825359 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature