Maternal Streptococcus agalactiae colonization in Europe: data from the multi-center DEVANI study.

ABSTRACT:

Introduction

Despite national guidelines and use of intrapartum antibiotic prophylaxis (IAP), Streptococcus agalactiae (group B streptococci (GBS)) is still a leading cause of morbidity and mortality in newborns in Europe and the United States. The European DEVANI (Design of a Vaccine Against Neonatal Infections) program assessed the neonatal GBS infection burden in Europe, the clinical characteristics of colonized women and microbiological data of GBS strains in colonized women and their infants with early-onset disease (EOD).

Methods

Overall, 1083 pregnant women with a GBS-positive culture result from eight European countries were included in the study. Clinical obstetrical information was collected by a standardized questionnaire. GBS strains were characterized by serolog

SUBMITTER: Lohrmann F 

PROVIDER: S-EPMC11825526 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature