Non-HACEK gram-negative bacilli infective endocarditis: data from a retrospective German cohort study.

ABSTRACT:

Purpose

Infective endocarditis caused by non-HACEK gram-negative bacilli (GNB-IE) is rare but associated with significant morbidity and case fatality. Evidence on optimal treatment and management is limited. We aimed to describe the characteristics and management of GNB-IE patients, investigating factors associated with disease acquisition and unfavorable outcomes.

Methods

We conducted a retrospective descriptive single-center study (tertiary care and referral hospital) between 2015 and 2021, including adult patients with definite GNB-IE. We reviewed demographic, clinical and microbiological data, focusing on predisposing factors, clinical outcomes and 1-year mortality.

Results

Of 1093 patients with probable or definite IE, 19 patients (median age 69 years) had defini

SUBMITTER: Dorfler J 

PROVIDER: S-EPMC11825580 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature