25 years of experience on the management of enterococcal infective endocarditis an observational study.

ABSTRACT:

Purpose

As they are effective and well tolerated, aminopenicillins are still the cornerstone for the treatment of enterococcal infections. Current treatment guidelines for infective endocarditis (IE) recommend combination treatments, which carry a higher risk of adverse effects and are based on limited in vitro and experimental data. The aim of this study was therefore to evaluate the treatments of enterococcal IE in real-life practice.

Methods

A total of 4121 episodes of enterococcal bloodstream infections, occurring between 1994 and 2019, were screened for the evidence of IE. Baseline characteristics, risk factors for complicated infections and treatment information were assessed and analyzed using Cox regression analysis.

Results

Overall, 80 (3.9%) IE episodes were

SUBMITTER: Schubert L 

PROVIDER: S-EPMC11825611 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature