Within-individual design for assessing true individual responses in resistance training-induced muscle hypertrophy.

ABSTRACT: Understanding interindividual variability in muscle hypertrophy in response to resistance training (RT) is a key focus of contemporary research. Common aims include identifying determinants of variability and recognizing individuals who do not respond to RT (i.e., non-responders). However, accurately identifying true individual responses (TIR) remains challenging due to the complex nature of muscle hypertrophy assessments. This complexity arises from distinguishing the TIR from natural variation in muscle mass over time and random measurement error in pre- and postintervention assessments. Existing studies have often overlooked this complexity, failing to employ experimental designs capable of isolating the TIR. Additionally, the reliance on random measurement error assessments based on gr

SUBMITTER: Chaves TS 

PROVIDER: S-EPMC11825802 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature