A realworld pharmacovigilance study of trazodone based on the FDA adverse event reporting system.

ABSTRACT: To explore and analyze the potential adverse event (AE) signals of trazodone, with reference to the safe clinical use of drugs. Based on the FDA Adverse Event Reporting System (FAERS), the AE data of trazodone were extracted from the first quarter of 2004 to the second quarter of 2024, and the extracted data were statistically analyzed using the method, to identify valid AE signals that met our judgment, compare them with those recorded in the authorized information for trazodone thereby identifying unexpected potential adverse reactions. A total of 5199 AE reports with trazodone as the main suspect were extracted, with a higher reported proportion of females (52.68%) than males (38.83%). Many reports (31.47%) did not provide age information, although for those reports with identifiable ag

SUBMITTER: Yu Y 

PROVIDER: S-EPMC11825867 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature