Clinician contributions to central nervous system-active polypharmacy among older adults with dementia in the United States.

ABSTRACT:

Background

Exposure to central nervous system (CNS)-active polypharmacy-overlapping exposure to three or more CNS-active medications-is potentially harmful yet common among persons living with dementia (PLWD). The extent to which these medications are prescribed to community-dwelling PLWD by individual clinicians versus distributed across multiple prescribers is unclear.

Methods

We identified community-dwelling Medicare beneficiaries with a dementia diagnosis and Medicare Parts A, B, and D coverage for at least one month in 2019. Using fill date and days' supply for prescriptions filled between January 1, 2019 and December 31, 2019, we identified beneficiaries exposed to CNS-active polypharmacy (i.e., >30 days of overlapping exposure to three or more antidepressant, antipsyc

SUBMITTER: Vordenberg SE 

PROVIDER: S-EPMC11826002 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature