<i>SMARCA4</i>/BRG1-deficient non-small cell lung cancer: clinical, imaging, pathological features, and follow-up results of 23 patients.

ABSTRACT:

Background

SMARCA4/BRG1-deficient non-small cell lung cancer (S/B-d NSCLC) is a rare subtype of non-small cell lung cancer (NSCLC). The aim of this study was to investigate the clinical, imaging, serum tumor marker, and pathological features of S/B-d NSCLC, particularly computed tomography (CT) and ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET/CT) scan features.

Methods

Our analysis included 23 patients with pathologically confirmed S/B-d NSCLC from January 2021 to December 2023. A retrospective analysis of clinical, serum tumor markers, imaging [including CT, FDG PET/CT, magnetic resonance imaging (MRI)], pathological features, treatment protocols, and follow-up results was performed. Independent samples t-tests

SUBMITTER: Wumener X 

PROVIDER: S-EPMC11826276 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature