A novel optimization of cone beam CT frequency for lung radiation therapy based on an image-guided radiation therapy protocol and patient classification method.

ABSTRACT:

Background

Cone beam computed tomography (CBCT) is a standard imaging modality in the management of lung cancer with radiation therapy. The optimal frequency of CBCT imaging during a course of radiotherapy is not currently strongly defined for many anatomical sites, including lung, and in clinical practice typically ranges from daily to weekly. There is a trade-off between clinical benefit derived from optimal soft tissue targeting with daily CBCT and the increased non-therapeutic dose that such imaging regimen entails. The aim of this study is to address this matter by proposing a new image-guided radiation therapy (IGRT) protocol and a patient classification method to achieve an optimal CBCT frequency for conventionally fractionated lung cancer radiation therapy.

Methods

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SUBMITTER: Zhou J 

PROVIDER: S-EPMC11826281 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature