Untargeted metabolomic analysis uncovers metabolic variability of four <i>Bifidobacterial</i> strains for probiotic development.

ABSTRACT: Bifidobacterium species are essential members of the human gut microbiota, playing crucial roles in host health. Variations in the metabolic functions of different Bifidobacterium strains can have distinct health effects, making it essential to understand their metabolic characteristics for the development of targeted probiotic formulations. In this study, we cultivated four selected Bifidobacterium strains from three species: Bifidobacterium animalis subsp. lactis BB-69, Bbm-19, Bifidobacterium brevis BX-18, and Bifidobacterium longum subsp. infantis B8762. We conducted an untargeted comparative metabolomic analysis to investigate the intracellular metabolic profile and functional activities of these strains. A total of 1,340 metabol

SUBMITTER: Liu K 

PROVIDER: S-EPMC11826312 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature