Regional Changes in the Fetal Telencephalic Wall Diffusion Metrics Across Late Second and Third Trimesters.

ABSTRACT: During the second and third trimesters of human gestation, the brain undergoes rapid neurodevelopment thanks to critical processes such as neuronal migration, radial glial scaffolding, and synaptic sprouting. Unfortunately, gathering high-quality MRI data on the healthy fetal brain is complex, making it challenging to understand this development. To address this issue, we conducted a study using motion-corrected diffusion tensor imaging (DTI) to analyze changes in the cortical gray matter (CP) and sub-cortical white matter (scWM) microstructure in 44 healthy fetuses between 23 and 36 weeks of gestational age. We automatically segmented these two tissues and parcellated them into eight regions based on anatomy, including the frontal, parietal, occipital, and temporal lobes, cingulate, senso

SUBMITTER: Calixto C 

PROVIDER: S-EPMC11826438 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature