Associations between per- and polyfluoroalkyl substances (PFAS) and female sexual function in a preconception cohort.

ABSTRACT:

Background

Female sexual function is important for sexual well-being, general health, fertility, and relationship satisfaction. Distressing impairments in sexual function, clinically recognized as female sexual dysfunction (FSD), can manifest as issues with interest/desire, arousal, orgasm, and pain during vaginal penetration. Some evidence suggests that exposure to endocrine-disrupting chemicals may adversely affect female sexual function, but associations for per- and polyfluoroalkyl substances (PFAS) have not been previously evaluated.

Objective

We investigated associations between serum PFAS concentrations and female sexual function among U.S. pregnancy planners.

Methods

We used cross-sectional data from participants from Pregnancy Study Online (PRESTO), a prospec

SUBMITTER: Schildroth S 

PROVIDER: S-EPMC11826513 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature