Hippocampal gray matter volume in young adulthood varies with adolescent alcohol use.

ABSTRACT: Adolescent substance use is linked with negative future outcomes (e.g., depression, anxiety, substance use disorder). Given that the brain undergoes significant maturation during adolescence, this developmental period may represent a time of particular vulnerability to substance use. Neuroimaging research has largely focused on heavy or binge patterns of substance use; thus, relatively less is known about the neural impact of a broader range of adolescent substance use. Characterizing the neural impact of a broader range of adolescent substance use may inform prevention and treatment efforts. The present study investigated relationships between adolescent substance use trajectories (i.e., alcohol, tobacco, and cannabis) and gray matter volume in young adulthood. Substance use was assessed

SUBMITTER: Purcell JB 

PROVIDER: S-EPMC11826516 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature