Chemospecific Heterostructure and Heteromaterial Assembly of Metal-Organic Framework Nanoparticles.

ABSTRACT: Nanoparticles of highly porous metal-organic frameworks (MOFs) are some of the most exciting nanomaterials under development, with potential applications that range from biomedicine and catalysis to adsorption technologies. However, our synthetic methodologies to functionalize and manipulate MOF nanoparticles (NPs) are less well developed than they might be. Here we create MOF NPs derivatized with hydrazone units on their exterior, enabling chemospecific reversible dynamic covalent modification of structures on the external surface. Pairwise combinations of nanometer-sized building blocks with complementary dynamic covalent surface units can be used to prepare heterostructure assemblies (i.e., two MOFs with different structures and morphologies) and heteromaterial assemblies (a MOF with a

SUBMITTER: Edward AK 

PROVIDER: S-EPMC11826876 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature