Development of an optode based on 2-amino-4-(4-nitrophenyl)diazenyl pyridine-3-ol and tri-<i>n</i>-octyl phosphine oxide for trace-level lead detection in complex samples.

ABSTRACT: A new selective optode has been created for the ultra-sensitive detection of lead ions at trace levels. The membrane is created by incorporating tri-n-octylphosphine oxide (TOPO), 2-amino-4-(4-nitrophenyl)diazenyl pyridine-3-ol (ANPDP), and sodium tetraphenylborate (Na-TPB) into a matrix of plasticized poly(vinyl chloride) (PVC) and o-nitrophenyloctyl ether (o-NPOE). ANPDP serves as a chromophore in this design, while TOPO promotes the formation of a complex between lead ions (Pb²⁺) and ANPDP, resulting in a cooperative interaction. The composition of the optode was optimized to achieve maximum sensor performance. The sensor exhibits a linear dynamic range from 6.0 to 160 ng mL^-1, with quantification and detection limits of 5.9 ng mL^-1

SUBMITTER: Alluhayb AH 

PROVIDER: S-EPMC11827045 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature