Electrophotocatalytic perfluoroalkylation by LMCT excitation of Ag(II) perfluoroalkyl carboxylates.

ABSTRACT: Molecular Ag(II) complexes are superoxidizing photoredox catalysts capable of generating radicals from redox-reticent substrates. In this work, we exploited the electrophilicity of Ag(II) centers in [Ag(bpy)₂(TFA)][OTf] and Ag(bpy)(TFA)₂ (bpy, 2,2'-bipyridine; OTf, CF₃SO₃^-) complexes to activate trifluoroacetate (TFA) by visible light-induced homolysis. The resulting trifluoromethyl radicals may react with a variety of arenes to forge C(sp²)-CF₃ bonds. This methodology is general and extends to other perfluoroalkyl carboxylates of higher chain length (R_FCO₂^-; R_F, CF₂CF₃ or CF₂CF₂CF₃). The photoredox reaction may be r

SUBMITTER: Campbell BM 

PROVIDER: S-EPMC11827047 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature